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Standardized Plant Extracts

Cnidium Monnieri Extract

Cnidium monnieri fruit extract standardized to Osthole (10%–98%, HPLC), supplied as a bulk marker-standardized ingredient for cosmetic and supplement formulation.

Chemical identity

CAS Number
484-12-8
Appearance
Brownish-yellow to off-white powder (purity-dependent)
Active Nutrition & EnergyBeauty & Skin
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Botanical Source

Botanical nameCnidium monnieri (L.) Cuss.
Part used果实

Technical Specifications

Botanical SourceFruits of _Cnidium monnieri (L.) Cuss._ · Pharmacopoeia Standard
Active Component ContentOsthole: 10% – 98% (Customizable); Ratio Extract: 10:1, 20:1, 30:1 · HPLC (Osthole); TLC (Ratio Extract)
Appearance10%-70%: Brownish-yellow to yellowish-green powder; 80%-98%: Light yellow to white crystalline powder · Organoleptic
Particle Size100% pass 80 mesh · Sieve Method
Loss on Drying≤ 8.0% · USP 36 <731>
Total Ash≤ 5.0% · USP 36 <281>
Heavy MetalsPb ≤ 2 ppm; Cd ≤ 2 ppm; As ≤ 1 ppm; Hg ≤ 0.1 ppm · Atomic Absorption Spectrometry
Microbial LimitsTotal Aerobic Bacteria ≤ 1000 CFU/g; Yeast & Mold ≤ 100 CFU/g; Coliforms/Salmonella: Negative · USP 36 <61> <62>
Solvent ResidueEthanol ≤ 500 ppm; No other organic residues · GC
Pesticide ResidueMeet cosmetic and pharmaceutical standards · GC-MS
Shelf Life24-36 months (proper storage) · Stability Test

Full batch-specific COA available on request.

Commercial Terms

MOQ
1 kg
Lead time
7-15 business days
Shelf life
24个月(按要求储存)
Sample
On request
Packaging
25kg/纸板桶;按客户要求包装
Storage
密闭,阴凉,防潮,避光。

Applications & Formulation Notes

Overview

Cnidium Monnieri Extract is derived from the dried fruit of Cnidium monnieri (L.) Cuss., mainly from Chinese planting bases, and is produced to relevant cosmetic and food/pharmaceutical-grade standards. We use low-temperature solvent extraction, membrane separation and spray-drying to maximize bioactive content while removing impurities and residues.

The key marker component is Osthole (10%–98%, HPLC), accompanied by bergapten, xanthotoxin and isoimperatorin. Advantages: traceable raw materials, customizable specifications (10:1 ratio extract through 98% Osthole), and full quality testing.

Key Active Compounds

The extract's profile is based on coumarin derivatives:

  • Osthole (CAS 484-12-8) — primary marker compound and basis of standardization.
  • Bergapten — associated coumarin constituent.
  • Xanthotoxin — associated coumarin constituent.
  • Isoimperatorin — associated coumarin constituent.

Researched Activities

The following reflect areas reported in published research and are provided for formulation context, not as product claims:

  • Antimicrobial research — osthole and related coumarins have been studied in antibacterial and antifungal assays.
  • Signaling-pathway research — osthole has been studied for modulation of NF-κB and related signaling in cell and animal models.
  • Other research interest — investigated in models relating to bone-metabolism and neuronal activity.

Application Areas

  • Cosmetics & personal care — topical formulations for sensitive-skin and skin-comfort positioning.
  • Dietary supplements — capsules and tablets.
  • Research & analytical — osthole reference material.

Why GreeneryBio

  • Traceable raw materials with customizable osthole specifications (10:1 to 98%).
  • Low-temperature processing for controlled residues.
  • COA, TDS and MSDS issued per batch.

Documents available

Documents are issued batch-specifically for ingredient evaluation and qualification. Request the set you need for your formulation.

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ISO 9001ISO 22000KosherHalalNon-GMO

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For B2B formulation and manufacturing use only. Information is provided for ingredient evaluation and does not constitute consumer health or disease claims.